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What other names is Jiaogulan known by?

Adaptogen, Adaptogène, Amachazuru, Dungkulcha, Fairy Herb, Ginseng du Sud, Gynostemma, Gynostemma pedatum, Gynostemma pentaphyllum, Herbe de l'Immortalité, Immortality Herb, Jiao Chu Lan, Jiao Gu Lan, Miracle Grass, Penta Tea, Plante de l'Immortalité, Southern Ginseng, Thé de l'Immortalité, Vitis pentaphylla, Xian Cao, Xianxao.

What is Jiaogulan?

Jiaogulan is a plant that grows wild in China. The leaf is used to make medicine. Jiaogulan is sometimes referred to as “Southern Ginseng” because it grows in south central China and is used in similar ways as ginseng.

Jiaogulan is used for high cholesterol, high blood pressure, and improving heart function. It is also used for strengthening the immune system, increasing stamina and endurance, increasing resistance to environmental stress (as an “adaptogen”), improving memory, and preventing hair loss.

Other uses include treatment of poor appetite, cough, chronic bronchitis, ongoing stomach pain (chronic gastritis), pain and swelling (inflammation), ulcers, constipation, stress, gallstones, obesity, cancer, diabetes, trouble sleeping (insomnia), backache, and pain.

Some people use jiaogulan as an anti-aging agent, antioxidant, and detoxifying agent.

Possibly Effective for...

Insufficient Evidence to Rate Effectiveness for...

More evidence is needed to rate the effectiveness of jiaogulan for these uses.

How does Jiaogulan work?

Jiaogulan contains substances that might help reduce cholesterol levels.

Are there safety concerns?

Jiaogulan is POSSIBLY SAFE when taken by mouth short-term (up to 4 months). It can cause some side effects such as severe nausea and increased bowel movements.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Jiaogulan is POSSIBLY UNSAFE when taken by mouth during pregnancy. One of the chemicals in jiaogulan has been linked to possible birth defects.

Not enough is known about the safety of jiaogulan during breast-feeding. Stay on the safe side and avoid use.

“Auto-immune diseases” such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Jiaogulan might cause the immune system to become more active. This could increase the symptoms of auto-immune diseases. If you have an auto-immune condition, it's best to avoid using jiaogulan until more is known.

Bleeding disorders: Jiaogulan may slow blood clotting. There is a concern that it might make bleeding disorders worse.

Surgery: Jiaogulan might slow blood clotting. There is some concern that it might increase the risk of bleeding during and after surgery. Stop using jiaogulan at least 2 weeks before a scheduled surgery.


How to Lower Your Cholesterol & Save Your Heart See Slideshow

Are there any interactions with medications?

Medications that decrease the immune system (Immunosuppressants)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Jiaogulan increases the activity of the immune system. By increasing the immune system jiaogulan might decrease the effectiveness of medications that decrease the activity of the immune system.

Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Jiaogulan might slow blood clotting. Taking jiaogulan along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), and others.

Dosing considerations for Jiaogulan.

The following doses have been studied in scientific research:


  • For high cholesterol: jiaogulan extract 10 mg three times daily.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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Reviewed on 9/17/2019

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