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Symptoms and Signs of Metastatic Melanoma Symptoms, Treatment, Prognosis, and Survival Rates

Doctor's Notes on Metastatic Melanoma Symptoms, Treatment, Prognosis, and Survival Rates

Metastatic melanoma is a type of cancer that starts in the cells in the skin that produce colored pigment called melanin and then spreads beyond its original skin location. Metastatic melanoma may spread through the bloodstream or the lymph system.

Symptoms of metastatic melanoma depend upon which organ system is involved and how much the tumor has grown there. Initially, metastatic melanoma may have no symptoms. Melanoma may spread to other areas of the skin and may be bluish-gray or flesh-colored nodules depending upon the amount of melanin in the tumor and depth in the skin. When metastatic melanoma spreads to the lymph nodes, symptoms may include swollen lymph glands, a string of nodules in the skin, or swelling of the extremities and enlarged glands. Symptoms of metastatic melanoma due to tumor metastasis into the liver may include weight loss, nausea, a swollen liver, and abnormal blood tests. Symptoms of metastatic melanoma due to tumor in the lungs may include shortness of breath, cough, and bloody sputum. Tumor in the brain may cause headaches, dizziness, and seizures. Tumor in bone may cause bone pain or unusual fractures.

Medical Author: John P. Cunha, DO, FACOEP
Medically Reviewed on 3/11/2019

REFERENCE:

Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.

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