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Periodic Limb Movement Disorder Topic Guide

Periodic Limb Movement Disorder Periodic Limb Movement Disorder: Periodic limb movement disorder (PLMD) is repetitive cramping or jerking of the legs during sleep. It's related to restless leg syndrome, but it is a distinct disorder. Learn about treatment and remedies.

Periodic Limb Movement Disorder Topic Guide - Medications and Vitamins


gabapentin Gabapentin

Gabapentin is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures ...learn more »

baclofen Baclofen

Baclofen is a muscle relaxer and an antispastic agent...learn more »

clonazepam Clonazepam

Clonazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that affects chemicals in the brain that may be unbalanced. Clonazepam is also a seizure medicine, ...learn more »

carbidopa Carbidopa

Carbidopa is used with another medicine called levodopa to treat the symptoms of Parkinson's disease (stiffness, tremors, spasms, poor muscle control). Symp...learn more »