Peripheral Vascular Disease (PVD) Topic Guide

Blood is supposed to clot to help repair a blood vessel that is injured. Clots or thrombi become a problem when they form inappropriately. There are a variety of illnesses and risk factors that can lead to blood clot formation such as atrial fibrillation, heart attack, strokes, transient ischemic attacks (TIAs), pulmonary embolism, deep vein thrombosis (DVT), and more. Diagnosis and treatment of blood clots depends on the cause and severity of the clot.

Blood cholesterol levels are measured by a simple blood test. Elevated LDL cholesterol (the "bad" cholesterol), and low levels of HDL cholesterol (the "good" cholesterol) levels, and high triglyceride levels puts a person at an increased risk for heart attack or stroke. The primary goal for a person with high triglycerides or cholesterol levels is to lower them with lifestyle changes like exercise, weight loss and diet changes to include more fiber, fruits and vegetables.

What causes diabetes, what tests diagnose it, and what is a good diabetic diet? Learn the signs of being diabetic, the treatments, and the differences between type 1 vs. type 2 diabetes. Type 1 diabetes (insulin dependent) can be caused by heredity, environmental factors, or ethnicity. Type 2 diabetes (non-insulin dependent) can be caused by high blood pressure, high lipid levels, high-fat diet, high alcohol intake, sedentary lifestyle, obesity, ethnicity, or age.

Be prepared to manage your diabetes, and control blood sugar and symptoms when you're sick, when you're at work or school, when traveling, during pregnancy, or during an emergency or natural disaster.

Deep vein thrombosis (blood clot in the leg, DVT) is a blood clot imbedded in one of the major veins of the lower body, including the legs, thighs, or pelvis. Disease and conditions that put you at risk of DVT are many, and include heart disease, heart attack, heart failure, pregnancy, estrogen therapy, prolonged periods of immobility, for example, sitting while traveling or confined to bed, trauma, being overweight, cancer, respiratory conditions, and advanced age. Symptoms of DVT include redness and warmth to the touch, leg swelling, pain or tenderness in the leg, redness or discoloration of the skin on the leg, leg cramps, edema, and pain. Treatment for a blood clot in the leg include medications, a vena cava filter, and graduated compression stockings. . You can prevent blood clots in the leg by moving around during prolonged periods of immobility, taking your medicine as your doctor has prescribed, getting up and moving as soon as possible after surgery or an illness (this lowers your chances of getting DVT), and exercising your leg muscles during long trips (particularly the lower leg muscles).

Atherosclerosis is the term referring to a hardening of the arteries caused by buildup of fat and cholesterol on the artery walls. The deposits, called plaque, can eventually block blood flow. Obesity, high cholesterol, age and a number of other factors put people at risk for atherosclerosis. Treatment may include lifestyle changes, surgery, and medication.

A heart attack is an interruption in blood flow to the heart muscle. Arterial plaque rupture is often the cause of a heart attack. Symptoms of a heart attack may include chest pain, shortness of breath, sweating, and nausea. Emergency heart catheterization and thrombolytic therapy may be used to treat a heart attack.

Coronary heart disease (CHD) is a group of different types of heart disease. Symptoms of heart disease depend on the cause and inclue chest pain or angina, shortness of breath, palpitations, and dizziness. Many conditions causes heart disease, for example, genetics, obesity, high cholesterol, and smoking. Treatment for heart disease depend on the cause and include diet and other lifestyle changes, medications, procedures, and surgery. The prognosis (outlook) and life span for someone with heart disease varies depending on the cause.

High blood pressure (hypertension) may be present in an individual, without any symptoms. Thus, it is called the "silent killer." Causes of high blood pressure include heart disease, kidney disease, tumors, birth control, alcohol, thyroid dysfunction, and birth control pills.Treatment of high blood pressure is generally through diet, exercise, and medication if necessary.

High cholesterol levels can lead to heart disease, stroke, angina, blood clot formation, stroke, and peripheral artery disease. Causes of high cholesterol include heredity, age, gender, stress, and lifestyle choices. Cholesterol levels can be reduced with lifestyle changes and medication if necessary (statins, fibrates, bile acid sequestrants, or niacin).

Lifestyle cholesterol management is important to lower your risk for heart disease, which includes: heart attack, stroke, and peripheral artery disease. Cholesterol management with lifestyle changes such as diet and exercise can effectively lower blood cholesterol levels in some individuals.

Statins are a class of drug prescribed for reducing blood cholesterol levels in individuals with high cholesterol. Examples of statins available include atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor, Altocor), pravastatin (Pravachol), pitavastatin (Livalo), simvastatin (Zocor), and rosuvastatin (Crestor). Common side effects include brown, discolored urine, vomiting, muscle weakness, leg pain, muscle soreness, and stomach cramps. Drug and food interactions, warnings and precautions, and serious side effects should be reviewed prior to taking any medication.

Stroke is a medical emergency. When a person has a stroke, part of the blood supply to the brain is cut off or greatly decreased. There are two main types of stroke, ischemic and hemorrhagic. Stroke symptoms include dizziness, sudden headache, weakness in an arm or leg on the same side, weakness in the muscles of the face, difficulty speaking, vision problems, and more. Treatment of stroke depends on the type and severity of the stroke suffered.

Cholesterol is a waxy, fat-like substance that is naturally present in the body. Diets high in fat, inactivity, and obesity contribute to high cholesterol. Some factors such as genetics are uncontrollable for having high cholesterol. You can lower your cholesterol levels naturally with lifestyle changes such as weight loss and control, exercise, diet, and quitting smoking. If these measures don't lower cholesterol enough a person may need to take cholesterol medications.

There are a variety of causes of leg pain. Some of the common causes include fractures, strains, sprains, bleeding, diseases such as gout, peripheral artery disease, and cancer. Leg pain can also be caused by blood clots, sciatica, neuropathy, joint pain, muscle injury, and skin abnormalities. Treatment of leg pain depends on the cause.

More than two-thirds of Americans are overweight, including at least one in five children. Nearly one-third are obese. Obesity is on the rise in our society because food is abundant and physical activity is optional. The safest way to lose weight is to eat less and exercise more. Treatment may also include medications, surgery, and behavior modification.

A pulmonary embolism (PE) is a blood clot in the lung. The clot typically comes from other areas of the body and travels to the lung, where it becomes lodged. Pulmonary embolism can cause serious problems, from shortness of breath to instantaneous death, depending on the nature of the clot.

Salmonella is a bacterial that can cause infectious diseases in humans. You get Salmonella by ingesting contaminated food or water and the infection is referred to as "food poisoning." Symptoms and signs of Salmonella infection include diarrhea, nausea, vomiting, and possibly fever. Sometimes Salmonella requires no treatment, other times a doctor may prescribe antibiotics.

Cigarette smoking remains the leading cause of death and illness among Americans. Effects of smoking can cause cancers, emphysema, bronchitis, COPD, chronic cough, and more. Smoking cessation includes nicotine replacement therapy and behavioral therapy.

Syphilis is a contagious bacterial infection transmitted most often through sexual intercourse. Flulike symptoms, body rash, and swollen lymph nodes. Late-phase syphilis attacks the heart, brain, skin, and bones. Late-stage syphilis is rare since the discovery of the antibiotic penicillin, which is used to treat this sexually transmitted disease (STD).

Syphilis, a sexually transmitted disease, is caused by a microscopic, wormlike bacterial organism called a spirochete. There are three stages of syphilis: The formation of the chancre is stage one. Stage two includes symptoms such as: hair loss, a sore throat, white patches in the nose, mouth, and vagina, fever, headaches, and a skin rash. The third stage can cause extensive damage to the internal organs and the brain, and can lead to death. Though early infection often resolves on its own, treatment usually varies based on the stage of the infection at the time of diagnosis.

Elevated or high triglycerides are a type of lipid disorder. Lipids are one type of fat transported through the bloodstream. High triglyceride levels may occur alone, or it may occur with other lipid disorders like high or low LDL "bad" cholesterol levels. Causes of high triglyceride levels include kidney and liver disease, alcoholism, obesity, medications, and thyroid problems. A triglyceride test determines the level of triglycerides in the blood. Treatment for elevated lipid levels include diet, lifestyle changes, and medication if necessary.

Learn the differences between type 1 and type 2 diabetes. Type 2 diabetes symptoms include excessive thirst and urination, and dehydration. Type 2 diabetes causes and risk factors include older age, obesity, lack of exercise, family history, and excess fat around waistline. Treatments for type 2 diabetes are weight loss, a healthy diet, exercise, and medications if necessary.

Vasculitis is inflammation and damage to blood vessels or blood vessel walls caused by certain diseases and conditions such as rheumatoid arthritis, lupus, giant cell arteritis, Kawasaki disease, hepatitis B and C, lymphoma, and more. Treatment depends on the cause of the underlying condition causing vasculitis.