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Pernicious Anemia (Vitamin B-12 Deficiency) (cont.)

Pernicious Anemia Treatment

Pernicious anemia can be treated by replenishing the vitamin B-12 supply in the body. If another underlying condition is responsible for vitamin B-12 deficiency, treatment must also be directed at that underlying process.

Self-Care at Home fo Pernicious Anemia (Vitamin B-12 Deficiency)

Be sure to follow the doctor's recommendations concerning diet and physical activity, and take all medications exactly as prescribed.

Medical Treatment fo Pernicious Anemia (Vitamin B-12 Deficiency)

Medical treatment is the mainstay of treatment for pernicious anemia and consists of vitamin B-12 preparations (see below) to replenish vitamin B-12 stores. Medical treatment is generally very effective, and symptoms may be improved with a few days of starting treatment.

Pernicious Anemia (Vitamin B-12 Deficiency) Medication

Pernicious anemia is typically treated with an intramuscular injection of 1000 micrograms (1 mg) of vitamin B-12 every day for one week, followed by 1 mg every week for four weeks and then 1 mg every month thereafter.

Alternative treatments include high-dose oral vitamin B-12, since a lower-efficiency absorption system for vitamin B-12 exists in the intestine that does not require the presence of IF. The dose required (1 to 2 milligrams/day) is more than 200 times higher than the minimum daily requirement for adults and is significantly higher than that available in most standard multivitamins and B-12 supplements. Nasal spray and sublingual (under the tongue) preparations of vitamin B-12 are also available.

Medically Reviewed by a Doctor on 12/16/2015

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