- What other names is Phenibut known by?
- What is Phenibut?
- How does Phenibut work?
- Are there safety concerns?
- Dosing considerations for Phenibut.
4-Amino-3-Phenylbutyric Acid, Acide 4-Amino-3-Phenylbutyrique, Acide Bêta-phényl-gamma-aminobutyrique, Agente Gabaérgico, B-Phenyl-Gamma-Aminobutyric Acid, Beta-Phenyl-GABA, Bêta-Phényl-GABA, Beta-phenyl-gamma-aminobutyric acid, Fenibut, Phénibut, Phenyl-GABA, Phényl-GABA.
Phenibut is a chemical similar to a brain chemical called gamma-aminobutyric acid (GABA). It is used as medicine.
Phenibut is used for anxiety, fear, trouble sleeping (insomnia), tension, stress, fatigue, post-traumatic stress disorder (PTSD), depression, alcoholism, and irregular heartbeat. It is also used for improving memory, learning, and thinking.
Insufficient Evidence to Rate Effectiveness for...
Phenibut is similar to the brain chemical called gamma-aminobutyric acid (GABA). Research in animals shows that it might decrease anxiety and have other effects on the body. But phenibut has not been studied in people, so no one knows whether it might work as a medicine.
There is not enough information to know if phenibut is safe. It has not been studied in people.
Special Precautions & Warnings:Pregnancy and breast-feeding: not enough is known about the use of phenibut during pregnancy and breast-feeding. stay on the safe side and avoid use.
The appropriate dose of phenibut depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for phenibut. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
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Tarakanov IA, Tarasova NN, Belova EA, Safonov VA. [Effect of phenibut on the respiratory arrest caused by serotonin]. Eksp Klin Farmakol 2006;69:28-32. View abstract.
Tiurenkov IN, Bagmetov MN, Epishina VV, et al. [Comparative evaluation of the neuroprotective activity of phenibut and piracetam under experimental cerebral ischemia conditions in rats]. Eksp Klin Farmakol 2006;69:19-22. View abstract.
Tiurenkov IN, Voronkov AV, Borodkina LE. [Effect of phenibut on the behavior of experimental animals under conditions of voluntary chronic alcoholism]. Eksp Klin Farmakol 2005;68:42-5. View abstract.
Ziablintseva EA. [The effect of GABA derivative phenibut on defensive conditioning and internal inhibition]. Zh Vyssh Nerv Deiat Im I P Pavlova 2006;56:236-41. View abstract.