Doctor's Notes on High Red Blood Cell Count (Polycythemia Vera)
Polycythemia refers to an elevated number of red blood cells (termed erythrocytes) in the circulation. This can occur either as a primary condition in which the bone marrow produces too many red blood cells (called polycythemia vera) or it may occur as a reaction to other diseases and conditions (such as hypoxia or low oxygen levels due to any reason) that drive the body to produce an increased number of red blood cells.
Symptoms and signs of polycythemia can be non-specific and may include weakness, fatigue, easy bruising, headache, joint pain, and dizziness. Other associated signs and symptoms can include itching, problems with blood clotting, bleeding, cough, or poor exercise tolerance. The particular signs and symptoms depend on the reason for the elevated red blood cell count.
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Blood Clots
Blood is supposed to clot to help repair a blood vessel that is injured. Clots or thrombi become a problem when they form inappropriately. There are a variety of illnesses and risk factors that can lead to blood clot formation such as atrial fibrillation, heart attack, strokes, transient ischemic attacks (TIAs), pulmonary embolism, deep vein thrombosis (DVT), and more. Diagnosis and treatment of blood clots depends on the cause and severity of the clot. -
Carbon Monoxide Poisoning
Carbon monoxide (CO) is a colorless, odorless gas produced by burning material containing carbon. Carbon monoxide kills nearly 400 people each year in the U.S. Early symptoms of carbon monoxide poisoning are headache, nausea, fatigue, and are often mistaken for the flu. If a person suspects they have been exposed to carbon monoxide poison, seek medical care emergently. -
Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a lung condition in which there is a long-lasting obstruction of the airways, and occurs with emphysema, chronic bronchitis, and/or asthma. Causes of COPD include cigarette smoking, exposure to secondhand smoke and environmental tobacco smoke, Alpha 1-antitrypsin deficiency, airway hyper-responsiveness, and air pollution. Symptoms of COPD include a productive cough and acute chest illness, shortness of breath, wheezing, heart failure, cyanosis, and weight loss. Treatment of COPD includes medications, oxygen therapy, surgery, and lung transplant. -
Complete Blood Count (CBC) Test and Results
Complete blood count (CBC) is one of the most common blood tests. The complete blood count test provides valuable information about the quantity of the different types of cells in the blood. The major cells in the blood are red blood cells, white blood cells, and platelets. Complete blood count can assist in diagnosing anemia, certain cancers, kidney problems, and allergic reactions. -
Congestive Heart Failure (CHF)
Congestive heart failure, or CHF, is a condition in which a person's heart is failing and it can't pump enough blood and oxygen to the body's tissues. Sometimes people with CHF don't know they have it. Early signs and symptoms symptoms are cough, shortness of breath, and having problems breathing; especially when lying down. And, if you have breathing problems like asthma, COPD, or emphysema and you think your condition is worsening. There are four stages of CHF. There's no cure for CHF, but treatments include drug therapy, diet, and lifestyle changes to relive symptoms and slow the progression of the disease. Life expectancy depends on existing medical problems, age, and overall health. -
Dehydration in Adults
Dehydration occurs when the loss of body fluids (mostly water), exceeds the amount that is taken in. Causes of dehydration include fever, vomiting, diarrhea, diseases (diabetes), impaired ability to drink, lack of access to safe drinking water, and injuries to the skin. Common symptoms of dehydration include dizziness, dry skin, headache, low urine output, tiredness, sleepiness, dry mouth, and increased thirst. Treatment of dehydration depends upon the severity of the condition. -
Dehydration in Children
Dehydration in children can result from not drinking enough liquids, vomiting, diarrhea, or combination of these conditions. Causes of dehydration in children include viral, bacterial, or parasitic infections, diabetes, and increased sweating, and others. Symptoms include sunken eyes, decrease in urination, no tears when crying, dry mouth, lethargy, and irritability. Treatment at home includes proper fluid replacement. Some cases of dehydration are so severe they may require hospitalization. -
DVT (Deep Vein Thrombosis Blood Clot in the Leg)
Deep vein thrombosis (blood clot in the leg, DVT) is a blood clot imbedded in one of the major veins of the lower body, including the legs, thighs, or pelvis. Disease and conditions that put you at risk of DVT are many, and include heart disease, heart attack, heart failure, pregnancy, estrogen therapy, prolonged periods of immobility, for example, sitting while traveling or confined to bed, trauma, being overweight, cancer, respiratory conditions, and advanced age. Symptoms of DVT include redness and warmth to the touch, leg swelling, pain or tenderness in the leg, redness or discoloration of the skin on the leg, leg cramps, edema, and pain. Treatment for a blood clot in the leg include medications, a vena cava filter, and graduated compression stockings. . You can prevent blood clots in the leg by moving around during prolonged periods of immobility, taking your medicine as your doctor has prescribed, getting up and moving as soon as possible after surgery or an illness (this lowers your chances of getting DVT), and exercising your leg muscles during long trips (particularly the lower leg muscles). -
Enlarged Spleen (Splenomegaly)
Enlarged spleen (splenomegaly) is generally caused by another condition such as cancers, bacterial or viral infections, immune disorders, and blood disorders. The most common symptom of an enlarged spleen is abdominal pain and bloating. Treatment for an enarged spleen is targeted toward the cause. -
Pulmonary Embolism
A pulmonary embolism (PE) is a blood clot in the lung. The clot typically comes from other areas of the body and travels to the lung, where it becomes lodged. Pulmonary embolism can cause serious problems, from shortness of breath to instantaneous death, depending on the nature of the clot. -
Pulmonary Hypertension
Pulmonary hypertension is an abnormally high pressure in the pulmonary arteries leading from the heart to the lungs. Primary pulmonary hypertension has no underlying condition that has caused this condition. Secondary pulmonary hypertension is caused by other underlying conditions. Treatment depends on the cause of the underlying condition, or the condition of primary pulmonary hypertension. -
Renal Cell Cancer
The kidneys, which filter excess water and waste from the blood, are susceptible to a number of different types of cancer, including renal cell cancer. This renal carcinoma develops in the small tubes in the kidneys' filtering system. Renal cell cancer may have a variety of environmental or hereditary causes, including smoking, obesity, occupational hazards and others. Renal cell cancer does not typically present symptoms early on, but symptoms include pain, blood in the urine, fatigue, malaise, night sweats, fevers and others. -
Sleep Apnea (Obstructive and Central)
There are two types of sleep apnea: obstructive sleep apnea (the most common type) and central sleep apnea. Sleep apnea can be caused by many factors such as strokes, heart failure, medications, or physical structures in the throat and mouth. Treatment range from medical devices to surgery.
REFERENCE:
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.