Symptoms and Signs of Proctitis

Medical Author:
Medically Reviewed on 9/15/2021

Doctor's Notes on Proctitis

Proctitis is an inflammation of the anus and/or the lining of the rectum (the last 6 inches of the rectum). Signs and symptoms include

  • pain during bowel movements,
  • soreness in the anal and/or rectal area,
  • involuntary spasms and cramping during bowel movements,
  • bleeding from the anal/rectal tissue,
  • discharge (pus),
  • small blisters around the anus,
  • anal warts, and
  • feeling that you can't completely empty your bowels.

Sexually transmitted diseases are the most common cause of proctitis. Other causes include

What Is the Treatment for Proctitis?

Treatments for proctitis depends on treating the underlying causes of this disease. The main causes with treatments are as follows:

  • Infections: antibiotics like doxycycline or antivirals like acyclovir
  • Radiation therapy: anti-inflammatory medications, antibiotics, stool softeners, dilation and removal of damaged tissue; bleeding control
  • Inflammatory bowel disease: medications to control rectal inflammation like prednisone or azathioprine; surgical removal of the damaged section of the GI tract


Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.