REM Sleep Behavior Disorder
REM Sleep Disorder Overview
Normal sleep has 2 distinct states: non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. NREM sleep is further subdivided into 3 stages. During REM sleep, rapid eye movements occur, breathing becomes more irregular, blood pressure rises, and there is loss of muscle tone (relative paralysis). However, the brain is highly active, and the electrical activity recorded in the brain by EEG during REM sleep is similar to that recorded during wakefulness. REM sleep is usually associated with dreaming. REM sleep accounts for 20-25% of the sleep period in most adults.
In a person with REM sleep behavior disorder (RBD), the paralysis that normally occurs during REM sleep is incomplete or absent, allowing the person to "act out" his or her dreams. RBD is classified under the general category of parasomnias. RBD is characterized by the acting out of dreams that are vivid, intense, and sometimes violent. Dream-enacting behaviors include talking, yelling, punching, kicking, sitting, jumping from bed, arm flailing, and grabbing. A common complaint includes a sleep-related injury An acute form may occur during withdrawal from alcohol or sedative-hypnotic drugs.
RBD is usually seen in middle-aged to elderly people (more often in men).
ABM Salah Uddin, MD
Erasmo A Passaro, MD
Francisco Talavera, PharmD, PhD
Stephen Berman, MD, PhD
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