REM Sleep Behavior Disorder (cont.)
IN THIS ARTICLE
What Are the Medications for REM Sleep Disorder?
Clonazepam (Klonopin) is highly effective in the treatment of REM sleep behavior disorder (RBD), relieving symptoms in nearly 90% of patients with little evidence of tolerance or abuse. The response usually begins within the first week, often on the first night. The initial dose is 0.5 mg at bedtime, with some persons requiring a rapid increase to 1 mg. With continued treatment for years, moderate limb twitching with sleep talking and more complex behaviors can reemerge. The treatment should be continued indefinitely, as violent behaviors and nightmares promptly recur with discontinuation of medications in almost all persons with RBD.
Other medications, such as tricyclic antidepressants, may be effective in some persons with RBD. However, tricyclics are also known to precipitate RBD in some patients.
Last Reviewed 12/8/2017
ABM Salah Uddin, MD
Erasmo A Passaro, MD
Francisco Talavera, PharmD, PhD
Stephen Berman, MD, PhD
Must Read Articles Related to REM Sleep Behavior Disorder
Patient Comments & Reviews
The eMedicineHealth doctors ask about REM Sleep Behavior Disorder:
REM Sleep Behavior Disorder - Treatment
What was the treatment for your REM sleep behavior disorder?
REM Sleep Behavior Disorder - Causes
What caused your REM sleep behavior disorder?