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Statins and Cholesterol (cont.)


Statins and Grapefruit Juice

Grapefruit juice may decrease the ability of the liver to metabolize some statins, for example, atorvastatin (Lipitor), simvastatin (Zocor), and lovastatin (Mevacor, Altocor), and should not be consumed at the same time as the statin medication is taken. Some doctors recommend avoiding any grapefruit juice. Also, and possibly more importantly, tell your doctor about any prescription and nonprescription medications you are taking.

Statins and Diabetes

Statins have been associated with increased fasting blood glucose (blood sugar) levels, HbA1C, and diabetes.

Statins and Memory Loss

Statins have been associated with memory loss, forgetfulness, amnesia, memory impairment, and confusion. Memory loss and other cognitive side effects are rare side effects of statins and they are not serious. Symptoms may begin 1 day to years after stating the statin and resolve within a median time of 3 weeks after the statin is stopped.

Statins are available as brands or generic formulations.

Effectiveness of Statins in Lowering Cholesterol

Statins may lower cholesterol levels by 20% to 60% by slowing the production of cholesterol and by increasing the liver's ability to remove LDL (low density lipoprotein) or bad cholesterol. Statins lower LDL levels more effectively than other types of drugs. They also modestly increase HDL (high-density lipoprotein) or good cholesterol levels and decrease total cholesterol and triglyceride levels.

Statins and Drug or Food Interactions

Statins and other medications may interact, causing serious side effects. These can include the following:

Health-care professionals or pharmacists will be able to give advice and direction regarding potential interactions between statins and other medications and dietary supplements.

Dangers of Statins

Individuals should not use statins if they:

REFERENCE: Rosenson, R. MD. "Statins: Actions, side effects, and administration." UpToDate. Updated: Feb 03, 2016.

Medically Reviewed by a Doctor on 11/21/2017
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