What Are Hand Tremors?
What Are the Symptoms and Signs of Hand Tremors and Types?
Two main categories can be recognized:
- normal (also called physiologic)
- abnormal (or pathologic)
The normal or physiological tremor is a fine, almost imperceptible, tremor that is difficult to see by the naked eye and does not interfere with activities. It can be seen in the fingers when the arms are outstretched. The frequency of the contractions is in the area of 8 to 13 cycles per minute. The cause of this tremor is not known, but it is not considered to be associated with any disease process.
The abnormal or pathological tremor it is more obvious and more visible to the naked eye. As such, it does interfere with everyday activities. The frequency of the contractions is in the area of 4 to 7 cycles per minute. In many instances this tremor is associated with defined medical conditions.
Most often the abnormal tremor is observed in the distal parts of the limbs (hands, fingers); however, every part of the body (such as the head, the tongue, the vocal cords, or the trunk) can be affected by the tremor.
The clinical distribution of the tremor might be different depending upon the medical condition associated with it and some individual factors. However, in a particular individual the quality and distribution of the tremor is very constant.
These abnormal tremors can be subclassified into the following categories:
A resting tremor (also call Parkinsonian tremor) is observed in a body part that is not active and is completely supported against gravity. It is a coarse, rhythmic tremor, often localized in the hands and forearms, but less frequently seen in other parts of the body and is observed when the limb is in a position of rest. Intentional movement might decrease the intensity of the tremor. However, the tremor disappears when the limbs are in extreme rest, as it is the case when the patient is sleeping.
This phenomenon is common to most of the tremors. In the hands, the tremors result in a peculiar "pill rolling" movement of the fingers, more obvious between the thumb and the index finger. Other parts of the body might also be affected. For example, the eyelids tend to flutter, and the jaw and the lips can flicker. When the legs are impaired it might result in gait (walking) problems. This tremor is most often seen as a manifestation of the Parkinson's syndrome.
Postural, or action tremor, is observed when muscles voluntarily contract. This tremor is exhibited with any attempt to keep the limbs or trunk in a particular position, for example to keep the arms outstretched. This type of tremor becomes worse when the limb is actively moved, for instance, when trying to drink from a cup. However, no tremor is observed when the limb is fully relaxed. This tremor is most often seen as a manifestation of essential tremor.
Intention (ataxic) tremor can be a very disabling type of tremor. It has some of the characteristics of the action tremor in the sense that it is triggered by movement; however, its main feature is that it occurs at the end of an action, when a fine, precise adjustment is needed. For example, when a person is asked to touch the tip of the nose, the early part of the action does not elicit the tremor, but as soon as the finger is near the nose and has to zero in on the tip of the nose, an irregular, rhythmic tremor with a frequency of 2 to 4 oscillations per minute is seen. Unlike action and resting tremor, the oscillations are in different planes and may persist even after the task is achieved. This type of tremor is mostly seen in conditions associated with the cerebellum or its neurological connections.
Rubral tremor is characterized by intense, violent movement. With this type of tremor, a patient's slight movement of the arms or attempts to maintain a static posture, like trying to keep the arms outstretched, results in an intense rhythmic "wing-beating" movement. It is also associated with some interruptions of the cerebellar connections.
This type of tremor is seen most often, among other conditions, in persons with multiple sclerosis.
In general, one particular tremor type is predominant and sometimes the only tremor present in a defined clinical condition, for example, resting tremor in Parkinson's disease or postural tremor in essential tremor. However, there are several individual variations, and it is not unusual for a patient with a defined clinical condition, for example Parkinson's disease, to have, besides the resting tremor typical of the disease, some degree of postural tremor.
What Are Symptoms and Signs Related to Hand Tremor?
Symptoms related to hand tremors include:
What Causes Hand Tremors?
The causes of tremor are very diverse. However, even though the list of potential causes is very extensive, a few conditions are predominant. The most important will be discussed here. The following are clinical conditions that may cause hand tremors and other types of tremors.
Familial and Essential Tremor
Familial and essential tremors are the most common conditions associated with action tremor. In the familial, or hereditary form, several members of the same family are affected. This is a genetically heterogeneous condition, and more than one gene might be involved.
The non-familial form is referred to as essential tremor because it is not associated with any other neurological condition. The term "benign essential tremor" has been used in reference to this tremor; however, this is misleading since the tremor can be very severe and disabling. The essential and the familial hereditary forms are similar in clinical presentation.
In some affected individuals the tremors start in infancy, however, more often they appear in the second and third decade of life and are most prevalent when a person is in his/her 60's.
It is seen in both sexes with similar frequency.
Most often, the first signs of tremors are seen in the arms, usually in both of them. The condition is chronic and, in many instances, progressive; as time goes by, other regions are involved including the head, neck, chin, and mouth. The tremor in the arms interferes with many activities such as eating and drinking.
Other clinical manifestations might be a tremulous voice, a continuous head movement in a vertical "yes, yes" or horizontal "no, no" pattern.
The legs are rarely affected.
The tremor might be severe enough to result in functional disability.
There is no diagnostic test that confirms the condition. The diagnosis is based on clinical findings. However some tests might be indicated to rule out other conditions.
Parkinsonian (rest) Tremor
This type of tremor is predominant in the Parkinsonian syndrome
The better known of these conditions is Parkinson's disease, a degenerative progressive disorder of the brain that predominantly affects a deep structure of the brain called the substantia nigra, located in the basal ganglia. The cause of the disease is unknown, the strongest associated risk factor being age. In some individuals, genetic factors might be important.
In Parkinson's disease the tremor is the most common initial sign. This is followed by:
gait disturbances, characterized by a shuffling gait and stooped posture;
stiffness in the muscles;
a general slowness in motor activities;
muscle pain; and
lack of dexterity.
In addition, the patients present with loss of facial expression and slowed speech with repetition of words. The symptoms progress slowly, and as the disease progresses the tremors are more prominent.
Other conditions with Parkinsonian Tremors
Several conditions in which Parkinsonian tremor might be an important feature include:
- Parkinson's disease (idiopathic form, cause unknown)
- Progressive supranuclear palsy
- Hungtington's disease
- Lewy body dementia
- Spinocerebellar degeneration
- Vascular parkinsonism
- Small ischemic infarcts in the brain (lacunar state)
- Neuroleptic agents
- reserpine (Harmonyl)
- Carbon monoxide intoxication
- Manganese intoxication
- Brain tumors
- Subdural hematomas
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