Symptoms and Signs of Testicular Cancer vs. Testicle Infection

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Medically Reviewed on 6/3/2019

Doctor's Notes on Testicular Cancer vs. Testicle Infection

Testicular cancer is the development of abnormal testicular cells that grow unregulated and may spread (metastasize) to other organs. Testicle infection is invasion or infection of testicular tissue usually by bacteria or viruses. Infections don't metastasize but may spread to other tissues. Both testicular cancers and infection may be curable, but both require very different treatments. A painless lump the size of a pea or marble next to a testicle is the most common sign of testicular cancer that is not found in testicular infections. Less common symptoms may include a sensation of testicular heaviness and shrinking and/or hardness. A testicle infection usually has symptoms of testicular swelling, redness, tenderness, and pain. Some patients may have fever, nausea, pain with urination, fatigue, headaches, and fatigue.

The causes of testicular cancer are unknown, but a major risk factor includes a history of undescended testicles. In contrast, there are many causes of testicle infections (for example, mumps virus, Coxsackievirus, E. coli, Staphylococcus, and many others).

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