Doctor's Notes on Uterine Cancer: Sarcoma
Uterine sarcoma is a rare disease where muscle cells or uterine supportive cells become malignant (cancer) cells. Signs and symptoms include vaginal bleeding that is not part of menstrual periods, bleeding after menopause, a mass in the vagina, abdominal pain or a feeling of fullness and/or increased urinary frequency. The disease can metastasize to other organs.
What causes uterine muscle and/or uterine supportive cells to become malignant is not known. However, risk factors associated with uterine sarcoma development are radiation to the pelvis, and treatment with tamoxifen for breast cancer.
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.