Symptoms and Signs of IgA Nephropathy (Berger's Disease)

Medical Author:
Medically Reviewed on 11/8/2021

Doctor's Notes on What Is IgA Nephropathy (Berger's Disease)?

Berger's disease (also known as IgA nephropathy) is renal disease that occurs when the protein IgA (immunoglobulin A) deposits or accumulates inside the renal filters (glomeruli) in the kidneys. It is considered an autoimmune kidney disease. It usually progresses slowly over years. Some patents may get complete disease remission while others develop end-stage kidney disease. There are many signs and symptoms that are non-specific that may slowly increase over time and may include the following:

Although the cause of Berger's disease is IgA accumulation in the kidneys, the underlying reason for its accumulation is unknown. Risk factors include the following:

  • Sex: It affects twice as many men as women in Western Europe and North America.
  • Ethnicity: It's more common in whites and Asians than blacks.
  • Age: It often develops between the late teens to late thirties.
  • Family history: It sometimes occurs in families.

What Are Treatments for Berger's Disease (IgA Nephropathy)?

Your doctor can help decide what treatments would best treat your condition.

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Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.