What Is Usually the First Symptom of Multiple Myeloma? Topic Guide

What Is Usually the First Symptom of Multiple Myeloma? What Is Usually the First Symptom of Multiple Myeloma?: Multiple myeloma does not cause symptoms in everyone. Bone pain, commonly in the back, hips, and skull is usually the first symptom of multiple myeloma. Other symptoms of multiple myeloma may include other bone problems (osteoporosis, bone weakness where there is a plasmacytoma, fractures), high blood levels of calcium (hypercalcemia), low counts of red blood cell (anemia), white blood cells (leukopenia), or plasma cells (thrombocytopenia); nervous system symptoms, nerve damage, thickened blood that slows blood flow to the brain, kidney problems, and infections (such as pneumonia).

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